RESEARCHER PROFILE

     Research Activity:

José Joaquín Merino Matín, PhD, Master. IdiPaz. UCM

Field of research: HIV-1 Neuropathogenesis

(Neuroimmunology/Neuroendocrinology/Chemokines/Neural Plasticiy/Neurodegenerative Diseases and inflammation)

UNED and UCM (School of Medecine, Madrid)
Schollar Research. USA. Postdoctoral fellow
CIB (CSIC). Centro de Investigaciones Biológicas.

Spanish Council Research
Hospital Donostia (Neurogenetics).Instituto Biodonostia. 
Conway Institute of Molecular Biology (Ireland).

UCD. Dept Pharmacology.

Biochemistry and Molecular Biology Dept. Complutense University of Madrid (UCM).





Chemokines and neuronal loss in the CNS of chronically stressed rats: effects on neural plasticity and memory formation

Role of corticosterone and cell adhesion molecules in neurodegeneration and plasticity

Role of chemokines in HIV-1 neuropathogenesis: cell adhesion molecules, chemokines and gp120 cell death in vitro (neurons/microglia)

Role of SDF1 and Fractalkine in the pathogenesis of CNS tumors: regulation by Growth hormone (GH) and Erythropoietin in Neuroblastome/Glioblastome cell line



Research Proyects

 (IP Merino JJ)

Neuroinflammation in patients carriers of PGRN gen mutation

Role of cell adhesion molecules in HIV-1 neuropathogenesis and cerebral ischemia: regulation by cerebrolysin.

Role of chemokine blockers in epilepsy:protective effects of valproate.

Neuroprotection by curcumine in stress and depression.

http://www.alzforum.org/com/res/detail.asp?id=%7BB682FEE6-0639-453E-9117-02578A1E910C%7D

 Neuroscience (Developmental Psychobiology), Neuropharmacology.

 Cellular and Molecular Neuroscience

Certificado de evaluación I3 positivo. Programa ¨Ramón y Cajal¨. Ministerio de Ciencia y Tecnología.

Premio Asociación Española Farmaceúticos Formulistas. ¨Ansyolitic effect of curcuime in depression: protective  and antiinflammatory effects against excitotoxicity in Neural Progenitor cells (NPC)¨

HIV Neuropathogenesis. Chemokines, cell adhesion molecules, and neuroinflammation in  neurodegenerative diseases

 ¨Role of chemokines in neurodegeneration and neural plasticity¨



CIBERNED. Neurodegenerative Disease Network

RENEVAS. Neurovascular Research Network

2 Patents and 100 Ingternational congress (Comunications)

30 Conferences (Hospital, University and CSIC)